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一． 个人基本信息
刘小云（1983- ），女，汉族，中共党员；博士；现为江汉大学生命科学学院教师
二． 主要学习工作经历
2010.09–2014.12: 华中农业大学生命科学技术学院 博士
2006.09–2014.12: 华中农业大学植物科学与技术学院硕士
2001.09–2005.07: 华中师范大学生命科学学院 学士
2015.01–2015.05：华中农业大学 研究助理
2019.08–2020.08: Michigan State University 访问学者
2015.06至今: 江汉大学 助理研究员
三． 主讲课程
暂无
四． 科学研究
1. 主要研究方向
表观修饰在植物发育与逆境响应中的调控机制研究
不同表观修饰因子之间的相互作用
表观修饰在农业生产以及药物开发中的应用
2. 主要科研项目
国家自然科学基金青年基金项目，项目编号：31600981，组蛋白H3K27me3修饰对水稻花粉发育的调控机理研究（主持）
武当特色中药研究湖北省重点实验室开放课题，项目编号：WDCM2020008,基于表观遗传学研究温度对珠子参道地性的影响（主持）
江汉大学高层次人才启动经费，项目编号：1019-06210002，水稻花粉发育的表观调控机理研究（主持）
国家留学基金委项目，项目编号：20908420106 （主持）
国家自然科学基金面上项目，项目编号：31371468，水稻冠根发育调节因子WOX11互作蛋白的鉴定及作用机理研究（第一参与人）
湖北省自然科学基金，项目编号：2016CFB630，基于第二代高通量测序技术研究干旱胁迫条件下拟南芥HDA9负调控和HDA6正调控作用机制（第一参与人）
国家自然科学基金面上项目，项目编号：31571256，水稻幼穗分化过程基因表达重编程的染色质基础研究（第二参与人）
国家自然科学基金青年基金项目，项目编号：31701737，致病相关分泌蛋白SS1G_08128在核盘菌致病过程中的作用及其机制研究（第一参与人）
国家自然科学基金青年项目，项目编号：31701100，组蛋白去乙酰化酶HDA9负调控拟南芥响应干旱和高温胁迫的分子机制研究（第一参与人）
国家自然科学基金面上项目，项目编号：22076065，基于DNA甲基转移酶介导的典型三价砷化合物直接与间接调控DNA甲基化的分子机制，（第一参与人）
3. 主要学术论文
第一作者或通信作者：
1. Zhou Chao # , Liu Xiaoyun # , Li Xinglei #, Zhou Hanlin, Wang Sijia, Yuan Zhu, Zhang Yonghong, Li Sanhe, You Aiqing, Zhou Lei*, He Zhengquan*. A Genome Doubling Event Reshapes Rice Morphology and Products by Modulating Chromatin Signatures and Gene Expression Profiling. Rice (N Y). 2021 Aug 4;14(1):72.
2. Zheng Lanlan#, Li Chen#, Ma Xueping, Zhou Hanlin, Liu Yuan, Wang Ping, Yang Huilai, Tamada Yosuke, Huang Ji, Wang Chunfei, Hu Zhubing, Wang Xuening, Wang Guodong, Li Haihong, Hu Juntao, Liu Xiaoyun*, Zhou Chao*, Zhang Yonghong*. Functional interplay of histone lysine 2-hydroxyisobutyrylation and acetylation in Arabidopsis under dark-induced starvation. Nucleic Acids Res. 2021 Jun 24:gkab536.
3.Xiaoyun Liu*#, Junling Luo #, Tiantian Li, Huilan Yang, Ping Wang, Lufang Su, Yu Zheng, Chun Bao, Chao Zhou*. SDG711 is involved in rice seed development through regulation of starch metabolism gene expression in coordination with other histone modifications. Rice, 2021 Mar 5;14(1):25.
4.Chao Zhou, Hanlin Zhou, Xueping Ma, Huilan Yang, Ping Wang, Guodong Wang, Lanlan Zheng, Yonghong Zhang* and Xiaoyun Liu*. Genome-Wide Identification and Characterization of Main Histone Modifications in Sorghum Decipher Regulatory Mechanisms Involved by mRNA and Long Noncoding RNA Genes. Journal of Agriculture and Food Chemistry, 2021 Feb 24;69(7):2337-2347.
5．Chao Zhou*, Zhu Yuan, Xueping Ma, Huilan Yang, Ping Wang, Lanlan Zheng, Yonghong Zhang* and Xiaoyun Liu*. Accessible chromatin regions and their functional interrelations with gene transcription and epigenetic modifications in sorghum genome. Plant Communications, 2020 Dec 31;2(1):100140.
6. Chongwei Tu, Tiantian Li, and Xiaoyun Liu*. Genetic and epigenetic regulatory mechanism of rice panicle development. 2018 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY AND BIOENGINEERING (8TH ICBB), AIP Conference Proceedings 2079, 020001 (2019).
7．Xiaoyun Liu#, Wei Wei#, Wenjun Zhu, Lufang Su, Zeyang Xiong, Man Zhou, Yu Zheng , Dao-Xiu Zhou *. Histone Deacetylase AtSRT1 Links Metabolic Flux and Stress Response in Arabidopsis. Molecular Plant, 2017, 10(12): 1510-1522.
8. Shaoli Zhou#, Xiaoyun Liu#, Chao Zhou#, Qiangwei Zhou, Yu Zhao, Guoliang Li, Dao-Xiu Zhou*, Cooperation between the H3K27me3 chromatin marker and non-CG methylation in epigenetic regulation. Plant Physiol, 2016, 172 (2) :1131-1141
9. Xiaoyun Liu#, Shaoli Zhou#, Wentao Wang, Yiran Ye, Yu Zhao,Qiutao Xu, Chao Zhou, Feng Tan, Saifeng Cheng, Dao-Xiu Zhou*, Regulation of Histone Methylation and Reprogramming of Gene Expression in the Rice Inflorescence Meristem, The Plant cell, 2015, 27(5): 1428-1444
10. Xiaoyun Liu, Chao Zhou, Yu Zhao, Shaoli Zhou, Wentao Wang, Dao-Xiu Zhou*, The Rice Enhancer of Zeste [E (z)] Genes SDG711 and SDG718 are respectively involved in Long Day and Short Day Signaling to Mediate the Accurate Photoperiod Control of Flowering time, Frontiers in Plant Science, 2014, 5:591
11．刘小云*，李晓，李腾飞，苏鲁方.水稻OsENO2-2基因过表达影响水稻开花期中国水稻科学，2018, 32（1）：12-22.
12．刘小云*，吴邦庭，邱璐. 植物逆境响应的表观遗传调控研究进展，江汉大学学报(自然科学版)，2018，46（2）：180-187
非第一或通讯作者：
1. Yu Zheng#*, Jingyu Ge#, Chun Bao, Wenwen Chang, Jingjing Liu, Jingjie Shao, Xiaoyun Liu, Lufang Su, Lei Pan, Dao-Xiu Zhou*. Histone deacetylase HDA9 and transcription factor WRKY53 are mutual antagonists in regulation of plant stress response. Molecular Plant, 2019, 13(4): 598-611
2.Yuan Shen#，Tingting Lei#，Xiaoyun Cui，Xiaoyun Liu，Shaoli Zhou，Yu Zheng，Florence Guérard，Emmanuelle Issakidis‐Bourguet，Dao‐Xiu Zhou*. Arabidopsis histone deacetylase HDA 15 directly represses plant response to elevated ambient temperature. The Plant Journal，2019，100(5): 991-1006
3. Jingjing Liu, Wenwen Chang, Lei Pan, Xiaoyun Liu, Lufang Su, Weiying Zhang, Qin Li & Yu Zheng. An Improved Method of Preparing High Efficiency Transformation Escherichia coli with Both Plasmids and Larger DNA Fragments. Indian Journal of Microbiology. 2018，58(4):448-456.
4. Saifeng Cheng, Feng Tan, Yue Lu, Xiaoyun Liu, Tiantian Li, Wenjia Yuan, Yu Zhao, Dao-Xiu Zhou *.WOX11 recruits a histone H3K27me3 demethylase to promote gene expression during shoot development in rice. Nucleic Acids Res. 2018, 46(5):2356-2369.
5. Yu Zheng*, Yue Ding, Xuan Sun, Sisi Xie, Dan Wang, Xiaoyun Liu, Lufang Su, Wei Wei1, Lei Pan and Dao-Xiu Zhou*, Histone deacetylase HDA9 negatively regulates salt and drought stress responsiveness in Arabidopsis, Journal of Experimental Botany, 2016，67 (6): 1703-1713
6. Tiantian Li, Xiangsong Chen, Xiaochao Zhong, Yu Zhao, Xiaoyun Liu, Shaoli Zhou, Saifeng Cheng, Dao-Xiu Zhou*, Jumonji C Domain Protein JMJ705-Mediated Removal of Histone H3 Lysine 27 Trimethylation Is Involved in Defense-Related Gene Activation in Rice, The Plant cell, 2013, 25(11): 4725–4736
7. Xiangsong Chen, Xiaoyun Liu, Yu Zhao, Dao-Xiu Zhou*, Histone H3K4me3 and H3K27me3 regulatory genes control stable transmission of an epimutation in rice, Scientific Reports, 2015, 5: 13251
8. Yu Zhao#*, Saifeng Cheng#,Yaling Song,Yulan Huang, Shaoli Zhou, Xiaoyun Liu, Dao-Xiu Zhou*, The Interaction between Rice ERF3 and WOX11 Promotes Crown Root Development by Regulating Gene Expression Involved in Cytokinin Signaling, The Plant Cell, 2015, 27(9): 2469–2483
9. Ning Zhu, Saifeng Cheng, Xiaoyun Liu, Hao Du, Mingqiu Dai, Dao-Xiu Zhou, Wenjing Yang, Yu Zhao*, The R2R3-type MYB gene OsMYB91 has a function in coordinating plant growth and salt stress tolerance in rice, Plant Science, 2015, 236:146-156
授权发明专利：
刘小云；李晓；李腾飞；周道绣影响水稻开花期和粒型的烯醇化酶基因OsENO2-2及其应用。专利号：ZL 201710284903.0
周道绣；刘小云；赵毓 组蛋白甲基转移酶基因在调控水稻开花期和穗型中的应用。专利号：ZL 201310079799.3。